Liver cancer is a type of cancer that begins in the cells of the liver. The liver is an intra-abdominal organ located in the right upper abdomen. Masses arising from the liver can range from a simple cyst to complex malignant lesions. More often, a malignant lesion in the liver is a metastasis (cancer that spreads to the liver) than a primary cancer.
Most commonly, metastatic liver lesions spread from primary cancers that arise from the gastrointestinal tract, lung, or breast. There are several types of primary liver cancer. The two most common types are hepatocellular carcinoma and cholangiocarcinoma.